Rapamycin Attenuates Cardiac Fibrosis in Experimental Uremic Cardiomyopathy by Reducing Marinobufagenin Levels and Inhibiting Downstream Pro-Fibrotic Signaling

Steven T. Haller; Yanling Yan; Christopher A. Drummond; Joe Xie; Jiang Tian; David J. Kennedy; Victoria Y. Shilova; Zijian Xie; Jiang Liu; Christopher J. Cooper; Deepak Malhotra; Joseph I Shapiro; Olga V. Fedorova; Alexei Y. Bagrov

Rapamycin Attenuates Cardiac Fibrosis in Experimental Uremic Cardiomyopathy by Reducing Marinobufagenin Levels and Inhibiting Downstream Pro-Fibrotic Signaling

Steven T. Haller
, Yanling Yan
, Christopher A. Drummond
, Joe Xie
, Jiang Tian
, David J. Kennedy
, Victoria Y. Shilova
, Zijian Xie
, Jiang Liu
, Christopher J. Cooper
, Deepak Malhotra
, Joseph I Shapiro
, Olga V. Fedorova
, Alexei Y. Bagrov

Marshall University

Research output: Contribution to journal › Article › peer-review

Original language	American English
Journal	Pharmaceutical Science and Research
State	Published - Jan 1 2016

Keywords

cardiac fibrosis
cardiomyopathy
cardiovascular diseases
fibrosis
heart failure

Disciplines

Medical Sciences
Medical Specialties
Medicine and Health Sciences

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Rapamycin Attenuates Cardiac Fibrosis in Experimental Uremic CardFinal published version, 1.35 MBLicense: Unspecified
Rapamycin Attenuates Cardiac Fibrosis in Experimental Uremic CardFinal published version, 1.35 MBLicense: Unspecified

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Haller, S. T., Yan, Y., Drummond, C. A., Xie, J., Tian, J., Kennedy, D. J., Shilova, V. Y., Xie, Z., Liu, J., Cooper, C. J., Malhotra, D., Shapiro, J. I., Fedorova, O. V., & Bagrov, A. Y. (2016). Rapamycin Attenuates Cardiac Fibrosis in Experimental Uremic Cardiomyopathy by Reducing Marinobufagenin Levels and Inhibiting Downstream Pro-Fibrotic Signaling. Pharmaceutical Science and Research.

@article{0a166440c62b4728902aa1abdb261817,

title = "Rapamycin Attenuates Cardiac Fibrosis in Experimental Uremic Cardiomyopathy by Reducing Marinobufagenin Levels and Inhibiting Downstream Pro-Fibrotic Signaling",

keywords = "cardiac fibrosis, cardiomyopathy, cardiovascular diseases, fibrosis, heart failure",

author = "Haller, \{Steven T.\} and Yanling Yan and Drummond, \{Christopher A.\} and Joe Xie and Jiang Tian and Kennedy, \{David J.\} and Shilova, \{Victoria Y.\} and Zijian Xie and Jiang Liu and Cooper, \{Christopher J.\} and Deepak Malhotra and Shapiro, \{Joseph I\} and Fedorova, \{Olga V.\} and Bagrov, \{Alexei Y.\}",

note = "Haller ST, Yan Y, Drummond CA, et al. Rapamycin attenuates cardiac fibrosis in experimental uremic cardiomyopathy by reducing marinobufagenin levels and inhibiting downstream pro‐fibrotic signaling. Journal of the American Heart Association 2016;5(10):e004106",

year = "2016",

month = jan,

day = "1",

language = "American English",

journal = "Pharmaceutical Science and Research",

}

TY - JOUR

T1 - Rapamycin Attenuates Cardiac Fibrosis in Experimental Uremic Cardiomyopathy by Reducing Marinobufagenin Levels and Inhibiting Downstream Pro-Fibrotic Signaling

AU - Haller, Steven T.

AU - Yan, Yanling

AU - Drummond, Christopher A.

AU - Xie, Joe

AU - Tian, Jiang

AU - Kennedy, David J.

AU - Shilova, Victoria Y.

AU - Xie, Zijian

AU - Liu, Jiang

AU - Cooper, Christopher J.

AU - Malhotra, Deepak

AU - Shapiro, Joseph I

AU - Fedorova, Olga V.

AU - Bagrov, Alexei Y.

N1 - Haller ST, Yan Y, Drummond CA, et al. Rapamycin attenuates cardiac fibrosis in experimental uremic cardiomyopathy by reducing marinobufagenin levels and inhibiting downstream pro‐fibrotic signaling. Journal of the American Heart Association 2016;5(10):e004106

PY - 2016/1/1

Y1 - 2016/1/1

KW - cardiac fibrosis

KW - cardiomyopathy

KW - cardiovascular diseases

KW - fibrosis

KW - heart failure

UR - https://mds.marshall.edu/sp_psr/118

M3 - Article

JO - Pharmaceutical Science and Research

JF - Pharmaceutical Science and Research

ER -

Rapamycin Attenuates Cardiac Fibrosis in Experimental Uremic Cardiomyopathy by Reducing Marinobufagenin Levels and Inhibiting Downstream Pro-Fibrotic Signaling

Keywords

Disciplines

Access to Document

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