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Chronic alcohol-induced liver injury and oxidant stress are decreased in cytochrome P4502E1 knockout mice and restored in humanized cytochrome P4502E1 knock-in mice

  • Yongke Lu
  • , Defeng Wu
  • , Xiaodong Wang
  • , Stephen C. Ward
  • , Arthur I. Cederbaum

Research output: Contribution to journalArticlepeer-review

Original languageAmerican English
JournalPharmacology, Physiology and Toxicology
StatePublished - Nov 1 2010

Keywords

  • Chronic alcohol
  • CYP2E1
  • Fatty liver
  • Oxidative stress
  • Hepatotoxicity
  • Free radicals

Disciplines

  • Medical Pharmacology
  • Medical Sciences
  • Medicine and Health Sciences

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