Research output per year
Research output per year
Personal profile
About
Dr. Susan H. Jackman is a Professor for Biochemistry and Microbiology.
Dr. Jackman studies how the immune system communicates with the body by molecules called cytokines. Disturbances in this communication may contribute to inappropriate immune responses, including autoimmunity. We have found that gene therapy with the cytokine, interleukin-7, can suppress autoimmune skin lesions in a mouse model. In a second area of study, we are investigating how the bacteria, Streptococcus agalactiae, which can cause life-threatening infections in the neonatal period, is able to recognize the human cytokine, interleukin-6, and respond by increasing its expression of stress/virulence genes.
Dr. Jackman studies how the immune system communicates with the body by molecules called cytokines. Disturbances in this communication may contribute to inappropriate immune responses, including autoimmunity. We have found that gene therapy with the cytokine, interleukin-7, can suppress autoimmune skin lesions in a mouse model. In a second area of study, we are investigating how the bacteria, Streptococcus agalactiae, which can cause life-threatening infections in the neonatal period, is able to recognize the human cytokine, interleukin-6, and respond by increasing its expression of stress/virulence genes.
Related documents
Research Interests
- Immunology
Disciplines
- Bacteria
- Bacterial Infections and Mycoses
- Bacteriology
- Biochemistry
- Biological Phenomena, Cell Phenomena, and Immunity
- Cell Biology
- Cells
- Cellular and Molecular Physiology
- Digestive, Oral, and Skin Physiology
- Immune System Diseases
- Medical Biochemistry
- Medical Cell Biology
- Medical Immunology
- Medical Microbiology
- Medical Physiology
- Microbiology
- Other Cell and Developmental Biology
- Physiological Processes
- Physiology
- Skin and Connective Tissue Diseases
Research output
- 6 Article
-
IL-7 Is a Critical Factor in Modulating Lesion Development in Skn-Directed Autoimmunity
Staton, P. J., Carpenter, A. B. & Jackman, S. H., Jul 1 2006, In: Biochemistry and Microbiology.Research output: Contribution to journal › Article › peer-review
-
Murine Epidermal Cell Antigen (Skn)-Directed Autoimmunity Induced by Transfer of CD4+ T Cells
Jackman, S. H., Keerthy, S. & Perry, G., Apr 1 2002, In: Biochemistry and Microbiology.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Serotyping Group B Streptococci in a Small Community Hospital: An Analysis of Distribution and Site of Isolation
Smith, J. M., Rexroth, J. A., Chaffin, D. G. & Jackman, S. H., Apr 1 2002, In: Biochemistry and Microbiology.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Differential Expression of Chemokines in a Mouse Model of Wound Healing
Jackman, S. H., Yoak, M. B., Keerthy, S. & Beaver, B. L., Apr 1 2000, In: Biochemistry and Microbiology.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Immunologic Effects of Gliotoxin in Rats: Mechanisms for Prevention of Autoimmune Diabetes Mellitus
Liu, H., Jackman, S. H., Driscoll, H. & Larsen, B., Oct 1 2000, In: Biochemistry and Microbiology.Research output: Contribution to journal › Article › peer-review
Open AccessFile
Prizes
-
Association of American Medical Colleges’ Medical Education Research Certificate
Jackman, S. H. (Recipient), 2024
Prize: Prize (including medals and awards)
-
Certificate of Teaching Excellence, Joan C Edwards School of Medicine, 2009
Jackman, S. H. (Recipient), 2009
Prize: Prize (including medals and awards)